Gene
mlc1
- ID
- ZDB-GENE-050419-145
- Name
- modulator of VRAC current 1
- Symbol
- mlc1 Nomenclature History
- Previous Names
-
- si:ch211-192n14.1
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Description
- Acts upstream of or within protein localization to cell surface. Located in cell-cell junction. Is expressed in nervous system and radial glial cell. Human ortholog(s) of this gene implicated in megalencephalic leukoencephalopathy with subcortical cysts 1. Orthologous to human MLC1 (modulator of VRAC current 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| megalencephalic leukoencephalopathy with subcortical cysts 1 | Alliance | Megalencephalic leukoencephalopathy with subcortical cysts 1 | 604004 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR033280 | Membrane protein MLC1 |
Domain Details Per Protein
| Protein | Length | Membrane protein MLC1 |
|---|---|---|
|
UniProtKB:A0A8M2BH89
|
394 | |
|
UniProtKB:A7MBY5
|
391 | |
|
UniProtKB:A0A8M9PQ91
|
395 |
Interactions and Pathways
No data available
Plasmids
No data available