Gene
nkx2.2b
- ID
- ZDB-GENE-050217-3
- Name
- NK2 homeobox 2b
- Symbol
- nkx2.2b Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to have DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in floor plate formation and ventral spinal cord interneuron differentiation. Predicted to localize to nucleus. Is expressed in several structures, including central nervous system; prechordal plate; presumptive ectoderm; primary interneuron; and trunk. Orthologous to human NKX2-2 (NK2 homeobox 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 34 figures from 15 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7162914 (19 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Homedomain-like superfamily | Homeobox, conserved site | Homeobox NK-like transcription regulators | Homeodomain | Homeodomain, metazoa |
|---|---|---|---|---|---|---|
|
UniProtKB:Q5BJA8
|
237 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
nkx2.2b-201
(1)
|
Ensembl | 1,634 nt |
Interactions and Pathways
No data available
Plasmids
No data available