Gene

cavin4b

ID

ZDB-GENE-041212-87

Name

caveolae associated protein 4b

Symbol

cavin4b Nomenclature History

Previous Names

murc (1)
murcb
wu:fc18g06
zgc:92239 (1)

Type

protein_coding_gene

Location

Chr: 24 Mapping Details/Browsers

Description

Involved in T-tubule organization and skeletal muscle fiber development. Predicted to localize to cytoplasm. Used to study muscular dystrophy. Is expressed in several structures, including adaxial cell; dorsal habenular nucleus; kidney; musculature system; and somite. Orthologous to human CAVIN4 (caveolae associated protein 4).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

13 figures from 7 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

MGC:92239 (8 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 6 figures from Housley et al., 2016
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With cavin4b Human Ortholog

No data available

Associated With cavin4b Via Experimental Models

Human Disease	Fish	Conditions	Citations
muscular dystrophy	cavin4b^s983/s983	standard conditions	Housley et al., 2016

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Family	IPR026752	Cavin family

Domain Details Per Protein

Protein	Length	Cavin family
UniProtKB:Q5PQY9 InterPro	318

Transcripts

Genome Browsers

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	cavin4b-201 (1) Ensembl	Ensembl		3,492 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

Name	Type	Antigen Genes	Isotype	Host Organism	Assay	Source	Citations
Ab1-murc	polyclonal	cavin4b		Rabbit	IHC	Sigma-Aldrich	2

Plasmids

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations