Gene
tfec
- ID
- ZDB-GENE-041210-21
- Name
- transcription factor EC
- Symbol
- tfec Nomenclature History
- Previous Names
-
- si:ch211-238e6.5
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including closure of optic fissure; hematopoietic stem cell homeostasis; and hemopoiesis. Predicted to be active in nucleus. Is expressed in several structures, including eye; immature eye; intermediate cell mass of mesoderm; neural crest; and post-vent region. Orthologous to human TFEC (transcription factor EC).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 15 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Helix-loop-helix DNA-binding domain superfamily | MiT/TFE transcription factors, C-terminal | MiT/TFE transcription factors, N-terminal | Myc-type, basic helix-loop-helix (bHLH) domain |
|---|---|---|---|---|---|
|
UniProtKB:A0A8M9PUG4
|
385 | ||||
|
UniProtKB:A0A8M6Z5C1
|
325 | ||||
|
UniProtKB:A0A8M2BBP2
|
395 | ||||
|
UniProtKB:Q1JQ62
|
396 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids