Gene
pcf11
- ID
- ZDB-GENE-041114-175
- Name
- PCF11 cleavage and polyadenylation factor subunit
- Symbol
- pcf11 Nomenclature History
- Previous Names
-
- im:6912257
- im:7138745 (1)
- wu:fc47a05
- zgc:175013
- zgc:92226
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to enable RNA polymerase II complex binding activity and mRNA binding activity. Acts upstream of or within regulation of termination of DNA-templated transcription. Predicted to be part of mRNA cleavage factor complex. Predicted to be active in cytoplasm. Orthologous to human PCF11 (PCF11 cleavage and polyadenylation factor subunit).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Kamieniarz-Gdula et al., 2019
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR002014 | VHS domain |
| Domain | IPR006569 | CID domain |
| Domain | IPR021605 | Pcf11, Clp1-ID |
| Domain | IPR047415 | Pcf11, CID domain |
| Domain | IPR048830 | Pre-mRNA cleavage complex 2 protein Pcf11, helical domain |
| Domain | IPR048832 | PCF11, charged region |
| Domain | IPR054127 | Pcf11, C-terminal domain |
| Family | IPR045154 | Protein PCF11-like |
| Homologous_superfamily | IPR008942 | ENTH/VHS |
Domain Details Per Protein
| Protein | Length | CID domain | ENTH/VHS | PCF11, charged region | Pcf11, CID domain | Pcf11, Clp1-ID | Pcf11, C-terminal domain | Pre-mRNA cleavage complex 2 protein Pcf11, helical domain | Protein PCF11-like | VHS domain |
|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q5U393
|
1457 |
Interactions and Pathways
No data available
Plasmids
No data available