Gene

pcf11

ID
ZDB-GENE-041114-175
Name
PCF11 cleavage and polyadenylation factor subunit
Symbol
pcf11 Nomenclature History
Previous Names
  • im:6912257
  • im:7138745 (1)
  • wu:fc47a05
  • zgc:175013
  • zgc:92226
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Description
Predicted to have RNA polymerase II complex binding activity and mRNA binding activity. Predicted to be involved in mRNA polyadenylation and termination of RNA polymerase II transcription. Predicted to localize to cytoplasm and mRNA cleavage factor complex. Orthologous to human PCF11 (PCF11 cleavage and polyadenylation factor subunit).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Kamieniarz-Gdula et al., 2019
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pcf11 Human Ortholog
No data available
Associated With pcf11 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR002014 VHS domain
Domain IPR006569 CID domain
Domain IPR021605 Pcf11, Clp1-ID
Domain IPR047415 Pcf11, CID domain
Domain IPR048830 Pre-mRNA cleavage complex 2 protein Pcf11, helical domain
Domain IPR048832 PCF11, charged region
Domain IPR054127 Pcf11, C-terminal domain
Family IPR045154 Protein PCF11-like
Homologous_superfamily IPR008942 ENTH/VHS
Domain Details Per Protein
Protein Length CID domain ENTH/VHS PCF11, charged region Pcf11, CID domain Pcf11, Clp1-ID Pcf11, C-terminal domain Pre-mRNA cleavage complex 2 protein Pcf11, helical domain Protein PCF11-like VHS domain
UniProtKB:Q5U393 1457
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA pcf11-201 (1) Ensembl 4,971 nt
mRNA pcf11-203 (1) Ensembl 1,246 nt
ncRNA pcf11-002 (1) Ensembl 747 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations