Gene

h2ax1

ID
ZDB-GENE-041010-42
Name
H2A.X variant histone family member 1
Symbol
h2ax1 Nomenclature History
Previous Names
  • h2afx1
  • zgc:101846 (1)
Type
protein_coding_gene
Location
Chr: 10 Mapping Details/Browsers
Description
Predicted to have DNA binding activity. Predicted to be involved in chromatin silencing; defense response to other organism; and membrane disruption in other organism. Predicted to localize to extracellular space and nuclear chromatin. Orthologous to several human genes including H2AC21 (H2A clustered histone 21).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With h2ax1 Human Ortholog
No data available
Associated With h2ax1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR032458 Histone H2A conserved site
Domain IPR007125 Histone H2A/H2B/H3
Domain IPR032454 Histone H2A, C-terminal domain
Family IPR002119 Histone H2A
Homologous_superfamily IPR009072 Histone-fold
Domain Details Per Protein
Protein Length Histone-fold Histone H2A Histone H2A conserved site Histone H2A, C-terminal domain Histone H2A/H2B/H3
UniProtKB:Q5XJK2 128
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA h2afx1-201 (1) Ensembl 909 nt
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab4-h2afx monoclonal IgG Rabbit
  • IHC
  • WB
Cell Signaling Technology, Inc.
11
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations