Gene

akr1a1a

ID
ZDB-GENE-040808-44
Name
aldo-keto reductase family 1, member A1a (aldehyde reductase)
Symbol
akr1a1a Nomenclature History
Previous Names
  • akr1a1
  • zgc:100940
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have alditol:NADP+ 1-oxidoreductase activity. Predicted to be involved in cellular detoxification of aldehyde. Predicted to localize to apical plasma membrane and cytosol. Orthologous to human AKR1A1 (aldo-keto reductase family 1 member A1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
5 figures from Qi et al., 2021
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With akr1a1a Human Ortholog
No data available
Associated With akr1a1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018170 Aldo/keto reductase, conserved site
Domain IPR023210 NADP-dependent oxidoreductase domain
Family IPR020471 Aldo-keto reductase
Family IPR044481 Aldo-keto reductase family 1 member A1
Homologous_superfamily IPR036812 NADP-dependent oxidoreductase domain superfamily
Domain Details Per Protein
Protein Length Aldo-keto reductase Aldo/keto reductase, conserved site Aldo-keto reductase family 1 member A1 NADP-dependent oxidoreductase domain NADP-dependent oxidoreductase domain superfamily
UniProtKB:Q6AZW2 324
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA akr1a1a-201 (1) Ensembl 1,098 nt
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-akr1a1a polyclonal Guinea pig
2
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations