Gene
akr1a1a
- ID
- ZDB-GENE-040808-44
- Name
- aldo-keto reductase family 1, member A1a (aldehyde reductase)
- Symbol
- akr1a1a Nomenclature History
- Previous Names
-
- akr1a1
- zgc:100940
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to have alditol:NADP+ 1-oxidoreductase activity. Predicted to be involved in cellular detoxification of aldehyde. Predicted to localize to apical plasma membrane and cytosol. Orthologous to human AKR1A1 (aldo-keto reductase family 1 member A1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7146346 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 5 figures from Qi et al., 2021
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR018170 | Aldo/keto reductase, conserved site |
| Domain | IPR023210 | NADP-dependent oxidoreductase domain |
| Family | IPR020471 | Aldo-keto reductase |
| Family | IPR044481 | Aldo-keto reductase family 1 member A1 |
| Homologous_superfamily | IPR036812 | NADP-dependent oxidoreductase domain superfamily |
Domain Details Per Protein
| Protein | Length | Aldo-keto reductase | Aldo/keto reductase, conserved site | Aldo-keto reductase family 1 member A1 | NADP-dependent oxidoreductase domain | NADP-dependent oxidoreductase domain superfamily |
|---|---|---|---|---|---|---|
|
UniProtKB:Q6AZW2
|
324 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
akr1a1a-201
(1)
|
Ensembl | 1,098 nt |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-akr1a1a | polyclonal | Guinea pig |
|
2 |
Plasmids
No data available