Gene
mipa
- ID
- ZDB-GENE-040801-41
- Name
- major intrinsic protein of lens fiber a
- Symbol
- mipa Nomenclature History
- Previous Names
-
- mip1
- aqp0a (1)
- zgc:100858
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Exhibits water channel activity. Involved in lens fiber cell morphogenesis and water transport. Predicted to localize to integral component of membrane and plasma membrane. Human ortholog(s) of this gene implicated in cataract and cataract 15 multiple types. Is expressed in eye; lens; lens fiber cell; and solid lens vesicle. Orthologous to human MIP (major intrinsic protein of lens fiber).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 11 figures from 8 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 14 figures from 5 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| cataract 15 multiple types | Alliance | Cataract 15, multiple types | 615274 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Aquaporin-like | Aquaporin transporter | Major intrinsic protein | Major intrinsic protein, conserved site |
|---|---|---|---|---|---|
|
UniProtKB:Q6DEI6
|
263 |
Interactions and Pathways
No data available
Plasmids
No data available