Gene

carm1

ID

ZDB-GENE-040724-77

Name

coactivator-associated arginine methyltransferase 1

Symbol

carm1 Nomenclature History

Previous Names

PRMT4 (1)
si:dkey-204f11.63
zgc:100805

Type

protein_coding_gene

Location

Chr: 3 Mapping Details/Browsers

Description

Predicted to enable several functions, including lysine-acetylated histone binding activity; protein-arginine N-methyltransferase activity; and transcription coactivator activity. Acts upstream of or within regulation of skeletal muscle fiber development. Predicted to be located in cytosol and nucleus. Predicted to be active in nuclear replication fork. Is expressed in nervous system; segmental plate; shield; and somite. Orthologous to human CARM1 (coactivator associated arginine methyltransferase 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

10 figures from 3 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

bc078292 (11 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 6 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With carm1 Human Ortholog

No data available

Associated With carm1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR020989	Histone-arginine methyltransferase CARM1, N-terminal
Domain	IPR055135	Protein arginine N-methyltransferase domain
Family	IPR025799	Protein arginine N-methyltransferase
Homologous_superfamily	IPR011993	PH-like domain superfamily
Homologous_superfamily	IPR029063	S-adenosyl-L-methionine-dependent methyltransferase superfamily

Domain Details Per Protein

Protein	Length	Histone-arginine methyltransferase CARM1, N-terminal	PH-like domain superfamily	Protein arginine N-methyltransferase	Protein arginine N-methyltransferase domain	S-adenosyl-L-methionine-dependent methyltransferase superfamily
UniProtKB:Q6DC04 InterPro	588
UniProtKB:A0A8M2BBB8 InterPro	582

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
aberrant processed transcript	carm1-203 (1) Ensembl	Ensembl	827 nt	Select Tool ZFIN BLAST
mRNA	carm1-201 (1) Ensembl	Ensembl	3,334 nt	Select Tool ZFIN BLAST
mRNA	carm1-202 (1) Ensembl	Ensembl	842 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

Name	Type	Antigen Genes	Isotype	Host Organism	Assay	Source	Citations
Ab1-carm1	polyclonal	carm1	IgG	Rabbit	WB	United States Biological	2

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations