Gene
egfl6
- ID
- ZDB-GENE-040718-157
- Name
- EGF-like-domain, multiple 6
- Symbol
- egfl6 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Predicted to have calcium ion binding activity and integrin binding activity. Involved in notochord development; positive regulation of sprouting angiogenesis; and regulation of Notch signaling pathway. Predicted to localize to membrane. Is expressed in several structures, including fin; median fin fold; pharyngeal arch; rhombomere; and somite. Orthologous to human EGFL6 (EGF like domain multiple 6).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 15 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb3 (18 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR018097 | EGF-like calcium-binding, conserved site |
| Domain | IPR000742 | EGF-like domain |
| Domain | IPR000998 | MAM domain |
| Domain | IPR001881 | EGF-like calcium-binding domain |
| Domain | IPR049883 | NOTCH1 EGF-like calcium-binding domain |
| Family | IPR052235 | Nephronectin domain-containing protein |
| Homologous_superfamily | IPR009030 | Growth factor receptor cysteine-rich domain superfamily |
| Homologous_superfamily | IPR013320 | Concanavalin A-like lectin/glucanase domain superfamily |
| PTM | IPR000152 | EGF-type aspartate/asparagine hydroxylation site |
Domain Details Per Protein
| Protein | Length | Concanavalin A-like lectin/glucanase domain superfamily | EGF-like calcium-binding, conserved site | EGF-like calcium-binding domain | EGF-like domain | EGF-type aspartate/asparagine hydroxylation site | Growth factor receptor cysteine-rich domain superfamily | MAM domain | Nephronectin domain-containing protein | NOTCH1 EGF-like calcium-binding domain |
|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q6DHG1
|
508 | |||||||||
|
UniProtKB:A0A8M6Z078
|
539 |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance