Gene

popdc1

ID
ZDB-GENE-040624-11
Name
popeye domain cAMP effector 1
Symbol
popdc1 Nomenclature History
Previous Names
  • pop1 (1)
  • bves
  • zgc:86887
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Predicted to have cAMP binding activity and structural molecule activity. Involved in several processes, including animal organ development; bicellular tight junction assembly; and skeletal myofibril assembly. Localizes to sarcolemma. Human ortholog(s) of this gene implicated in autosomal recessive limb-girdle muscular dystrophy type 2X. Is expressed in several structures, including EVL; cardiovascular system; eye; integument; and optic vesicle. Orthologous to human BVES (blood vessel epicardial substance).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
13 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
14 figures from 5 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With popdc1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
autosomal recessive limb-girdle muscular dystrophy type 2X Alliance Muscular dystrophy, limb-girdle, autosomal recessive 25 616812
Associated With popdc1 Via Experimental Models
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Homologous_superfamily IPR014710 RmlC-like jelly roll fold
Homologous_superfamily IPR018490 Cyclic nucleotide-binding domain superfamily
Domain Details Per Protein
Protein Length Cyclic nucleotide-binding domain superfamily RmlC-like jelly roll fold
UniProtKB:G9HVJ5 352
UniProtKB:Q5PQZ7 352
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA bves-201 (1) Ensembl 1,771 nt
mRNA bves-202 (1) Ensembl 1,798 nt
mRNA bves-203 (1) Ensembl 1,827 nt
mRNA bves-204 (1) Ensembl 3,020 nt
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-bves polyclonal Rabbit
  • IHC
2
Ab2-bves polyclonal Rabbit
  • IHC
Sigma-Aldrich
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations