Gene
waslb
- ID
- ZDB-GENE-040426-718
- Name
- WASP like actin nucleation promoting factor b
- Symbol
- waslb Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Predicted to enable actin binding activity. Acts upstream of or within dermal bone morphogenesis; myeloid cell differentiation; and myoblast fusion. Predicted to be located in cytoplasm; cytoskeleton; and nucleus. Predicted to be active in plasma membrane. Is expressed in several structures, including EVL; notochord; pectoral fin bud; periderm; and retina. Orthologous to human WASL (WASP like actin nucleation promoting factor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 9 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55478 (10 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000095 | CRIB domain |
| Domain | IPR000697 | WH1/EVH1 domain |
| Domain | IPR003124 | WH2 domain |
| Domain | IPR033927 | WASP family, EVH1 domain |
| Homologous_superfamily | IPR011026 | Actin nucleation-promoting factor WAS, C-terminal |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
| Homologous_superfamily | IPR036936 | CRIB domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Actin nucleation-promoting factor WAS, C-terminal | CRIB domain | CRIB domain superfamily | PH-like domain superfamily | WASP family, EVH1 domain | WH1/EVH1 domain | WH2 domain |
|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9Q5U1 | InterPro | 490 | |||||||
| UniProtKB:Q6NYX7 | InterPro | 518 | |||||||
| UniProtKB:A0A8M3AR38 | InterPro | 458 | |||||||
| UniProtKB:A0A8M2BBM4 | InterPro | 510 |
Interactions and Pathways
No data available
Plasmids
No data available