Gene
srsf2a
- ID
- ZDB-GENE-040426-2706
- Name
- serine and arginine rich splicing factor 2a
- Symbol
- srsf2a Nomenclature History
- Previous Names
-
- sfrs2
- srsf2
- hm:zeh0252
- wu:fb51a05
- wu:fk59b08
- zgc:56283
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to have RNA binding activity. Predicted to be involved in mRNA cis splicing, via spliceosome and regulation of alternative mRNA splicing, via spliceosome. Predicted to localize to cytoplasm and nuclear speck. Human ortholog(s) of this gene implicated in acute myeloid leukemia and myelodysplastic syndrome. Orthologous to several human genes including SRSF2 (serine and arginine rich splicing factor 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:56283 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000504 | RNA recognition motif domain |
| Domain | IPR003954 | RNA recognition motif domain, eukaryote |
| Family | IPR051106 | RNA-binding and splicing regulatory protein |
| Homologous_superfamily | IPR012677 | Nucleotide-binding alpha-beta plait domain superfamily |
| Homologous_superfamily | IPR035979 | RNA-binding domain superfamily |
Domain Details Per Protein
| Protein | Length | Nucleotide-binding alpha-beta plait domain superfamily | RNA-binding and splicing regulatory protein | RNA-binding domain superfamily | RNA recognition motif domain | RNA recognition motif domain, eukaryote |
|---|---|---|---|---|---|---|
|
UniProtKB:Q7ZV13
|
225 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| aberrant processed transcript |
srsf2a-202
(1)
|
Ensembl | 582 nt | ||
| aberrant processed transcript |
srsf2a-205
(1)
|
Ensembl | 567 nt | ||
| aberrant processed transcript |
srsf2a-206
(1)
|
Ensembl | 603 nt | ||
| aberrant processed transcript |
srsf2a-208
(1)
|
Ensembl | 908 nt | ||
| mRNA |
srsf2a-201
(1)
|
Ensembl | 1,776 nt | ||
| mRNA |
srsf2a-204
(1)
|
Ensembl | 1,151 nt | ||
| mRNA |
srsf2a-207
(1)
|
Ensembl | 855 nt | ||
| mRNA |
srsf2a-209
(1)
|
Ensembl | 707 nt | ||
| mRNA |
srsf2a-211
(1)
|
Ensembl | 788 nt | ||
| ncRNA |
srsf2a-002
(1)
|
Ensembl | 1,024 nt | ||
| ncRNA |
srsf2a-010
(1)
|
Ensembl | 636 nt |
Interactions and Pathways
No data available
Plasmids
No data available