Gene

wrnip1

ID

ZDB-GENE-040426-2415

Name

WRN helicase interacting protein 1

Symbol

wrnip1 Nomenclature History

Previous Names

zgc:85976 (1)

Type

protein_coding_gene

Location

Chr: 2 Mapping Details/Browsers

Description

Predicted to have enzyme activator activity and single-stranded DNA helicase activity. Predicted to be involved in DNA-dependent DNA replication and regulation of DNA repair. Predicted to localize to nucleus. Orthologous to human WRNIP1 (WRN helicase interacting protein 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Babu et al., 2022

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With wrnip1 Human Ortholog

No data available

Associated With wrnip1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR003593	AAA+ ATPase domain
Domain	IPR003959	ATPase, AAA-type, core
Domain	IPR006642	Rad18, zinc finger UBZ4-type
Domain	IPR021886	MgsA AAA+ ATPase C-terminal
Domain	IPR032423	AAA C-terminal domain
Family	IPR051314	AAA ATPase RarA/MGS1/WRNIP1
Homologous_superfamily	IPR008921	DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase