Gene
wls
- ID
- ZDB-GENE-040426-2161
- Name
- Wnt ligand secretion mediator
- Symbol
- wls Nomenclature History
- Previous Names
-
- gpr177
- id:ibd2010
- sb:cb610
- wu:fb36d04
- wu:fb44d10
- wu:fb50c06
- zgc:64091
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to have Wnt-protein binding activity. Involved in several processes, including animal organ development; chondrocyte activation; and chondrocyte proliferation. Predicted to localize to endomembrane system and integral component of organelle membrane. Is expressed in several structures, including central nervous system; head; inner ear; midbrain neural keel; and neural tube. Orthologous to human WLS (Wnt ligand secretion mediator).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 23 figures from 9 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb610 (29 images)
Wild Type Expression Summary
- All Phenotype Data
- 25 figures from 6 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Zaki syndrome | Alliance | Zaki syndrome | 619648 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Protein wntless | Wntless, GOLD domain | Wntless-like, transmembrane domain |
|---|---|---|---|---|
|
UniProtKB:Q7T357
|
542 | |||
|
UniProtKB:F2Z4U3
|
542 |
Interactions and Pathways
No data available
Plasmids
No data available