Gene

fbl

ID
ZDB-GENE-040426-1936
Name
fibrillarin
Symbol
fbl Nomenclature History
Previous Names
  • fb37g12
  • wu:fb37g12
  • zgc:56145
  • zgc:77130 (1)
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Predicted to have RNA binding activity; histone-glutamine methyltransferase activity; and rRNA methyltransferase activity. Involved in neurogenesis. Localizes to nucleolus. Is expressed in several structures, including alar plate midbrain region; digestive system; immature eye; musculature system; and nervous system. Orthologous to several human genes including FBL (fibrillarin).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
10 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
11 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With fbl Human Ortholog
No data available
Associated With fbl Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR020813 Fibrillarin, conserved site
Family IPR000692 rRNA 2'-O-methyltransferase fibrillarin-like
Homologous_superfamily IPR029063 S-adenosyl-L-methionine-dependent methyltransferase superfamily
Domain Details Per Protein
Protein Length Fibrillarin, conserved site rRNA 2'-O-methyltransferase fibrillarin-like S-adenosyl-L-methionine-dependent methyltransferase superfamily
UniProtKB:Q7ZTZ4 317
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA fbl-201 (1) Ensembl 1,436 nt
ncRNA fbl-002 (1) Ensembl 456 nt
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-fbl monoclonal IgG1 Mouse
  • IHC
  • WB
Abcam plc
14
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations