Gene
fscn2b
- ID
- ZDB-GENE-040426-1740
- Name
- fascin actin-bundling protein 2b, retinal
- Symbol
- fscn2b Nomenclature History
- Previous Names
-
- fscn1l
- fscn2
- zgc:73272
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to have actin filament binding activity. Predicted to be involved in actin filament bundle assembly; cell migration; and establishment or maintenance of cell polarity. Predicted to localize to cytoplasm. Human ortholog(s) of this gene implicated in retinitis pigmentosa and retinitis pigmentosa 30. Is expressed in eye; hair cell anterior macula; otic vesicle; retina; and retinal photoreceptor layer. Orthologous to human FSCN2 (fascin actin-bundling protein 2, retinal).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:73272 (7 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| retinitis pigmentosa 30 | Alliance | Retinitis pigmentosa 30 | 607921 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Actin-crosslinking | Fascin | Fascin domain | Fascin, metazoans |
|---|---|---|---|---|---|
|
UniProtKB:B2LT50
|
490 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
fscn2b-201
(1)
|
Ensembl | 3,389 nt |
Interactions and Pathways
No data available
Plasmids
No data available