Gene

psmd6

ID
ZDB-GENE-040426-1038
Name
proteasome 26S subunit, non-ATPase 6
Symbol
psmd6 Nomenclature History
Previous Names
  • vov (1)
  • zgc:56471 (1)
Type
protein_coding_gene
Location
Chr: 11 Mapping Details/Browsers
Description
Predicted to have enzyme regulator activity. Involved in lens fiber cell differentiation and proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to localize to proteasome regulatory particle. Is expressed in ciliary marginal zone; head; and lens epithelium. Orthologous to human PSMD6 (proteasome 26S subunit, non-ATPase 6).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
6 figures from Imai et al., 2010
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With psmd6 Human Ortholog
No data available
Associated With psmd6 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000717 Proteasome component (PCI) domain
Domain IPR045135 26S proteasome regulatory subunit Rpn7, N-terminal
Domain IPR049549 26S proteasome regulatory subunit RPN7/PSMD6, C-terminal helix
Family IPR019585 26S proteasome regulatory subunit Rpn7/COP9 signalosome complex subunit 1
Homologous_superfamily IPR011990 Tetratricopeptide-like helical domain superfamily
Homologous_superfamily IPR036390 Winged helix DNA-binding domain superfamily
Domain Details Per Protein
Protein Length 26S proteasome regulatory subunit Rpn7/COP9 signalosome complex subunit 1 26S proteasome regulatory subunit Rpn7, N-terminal 26S proteasome regulatory subunit RPN7/PSMD6, C-terminal helix Proteasome component (PCI) domain Tetratricopeptide-like helical domain superfamily Winged helix DNA-binding domain superfamily
UniProtKB:Q7ZWE5 386
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA psmd6-201 (1) Ensembl 1,430 nt
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-psmd6
  • WB
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations