Gene

zar1

ID

ZDB-GENE-030818-1

Name

zygote arrest 1

Symbol

zar1 Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 20 Mapping Details/Browsers

Description

Exhibits mRNA binding activity involved in posttranscriptional gene silencing. Involved in negative regulation of translation; positive regulation of oogenesis; and translation. Localizes to protein-containing complex. Is expressed in gonad; liver; oocyte stage I; and oocyte stage II. Orthologous to human ZAR1 (zygote arrest 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

5 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 8 figures from Miao et al., 2017
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With zar1 Human Ortholog

No data available

Associated With zar1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR027377	ZAR1/RTP1-5-like, 3CxxC-type zinc finger
Family	IPR026775	Zygote arrest protein 1

Domain Details Per Protein

Protein	Length	ZAR1/RTP1-5-like, 3CxxC-type zinc finger	Zygote arrest protein 1
UniProtKB:Q561Z6 InterPro	329
UniProtKB:Q7T3T8 InterPro	329

Transcripts

Genome Browsers

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	zar1-201 (1) Ensembl	Ensembl		1,193 nt	Select Tool
ncRNA	zar1-002 (1) Ensembl	Ensembl		604 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

Name	Type	Antigen Genes	Isotype	Host Organism	Assay	Source	Citations
Ab1-zar1		zar1		Rabbit	WB		1

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations