Gene

rtn4a

ID

ZDB-GENE-030710-1

Name

reticulon 4a

Symbol

rtn4a Nomenclature History

Previous Names

rtn4
Nogo-B (1)
nogo (1)
wu:fb17a02
wu:fb22f12
wu:fd61a07
zgc:92163

Type

protein_coding_gene

Location

Chr: 6 Mapping Details/Browsers

Description

Involved in several processes, including mesenchymal to epithelial transition; nervous system development; and sensory system development. Predicted to localize to endoplasmic reticulum; endoplasmic reticulum membrane; and integral component of membrane. Is expressed in several structures, including heart; liver; muscle; nervous system; and pectoral fin. Orthologous to human RTN4 (reticulon 4).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

11 figures from 9 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 9 figures from 5 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With rtn4a Human Ortholog

No data available

Associated With rtn4a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR003388	Reticulon
Family	IPR046964	Reticulon 1-4

Domain Details Per Protein

Protein	Length	Reticulon	Reticulon 1-4
UniProtKB:Q4G5V9 InterPro	212
UniProtKB:F1QT89 InterPro	196
UniProtKB:Q4G5W2 InterPro	322

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	rtn4a-201 (1) Ensembl	Ensembl	2,079 nt	Select Tool
mRNA	rtn4a-202 (1) Ensembl	Ensembl	2,138 nt	Select Tool
mRNA	rtn4a-203 (1) Ensembl	Ensembl	1,647 nt	Select Tool
mRNA	rtn4a-204 (1) Ensembl	Ensembl	1,887 nt	Select Tool
ncRNA	rtn4a-005 (1) Ensembl	Ensembl	573 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

Name	Type	Antigen Genes	Isotype	Host Organism	Assay	Source	Citations
Ab1-rtn4a	polyclonal	rtn4a	IgG	Rabbit	IHC OTHR WB		4

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations