Gene
adarb1b
- ID
- ZDB-GENE-030219-15
- Name
- adenosine deaminase RNA specific B1b
- Symbol
- adarb1b Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Predicted to have double-stranded RNA adenosine deaminase activity; double-stranded RNA binding activity; and tRNA-specific adenosine deaminase activity. Predicted to be involved in RNA processing and adenosine to inosine editing. Predicted to localize to cytoplasm and nucleolus. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis. Is expressed in blood island; blood vessel; central nervous system; and immature eye. Orthologous to human ADARB1 (adenosine deaminase RNA specific B1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Neurodevelopmental disorder with hypotonia, microcephaly, and seizures | 618862 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | ADAR2, first double-stranded RNA binding domain | ADAR2, second double-stranded RNA binding domain | Adenosine deaminase/editase | Double-stranded RNA-binding domain |
|---|---|---|---|---|---|
|
UniProtKB:A0A8M9Q590
|
750 | ||||
|
UniProtKB:E9QJK5
|
699 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
adarb1b-201
(1)
|
Ensembl | 2,471 nt | ||
| mRNA |
adarb1b-202
(1)
|
Ensembl | 2,457 nt | ||
| mRNA |
adarb1b-203
(1)
|
Ensembl | 2,199 nt |
Interactions and Pathways
No data available
Plasmids
No data available