Gene
sgcb
- ID
- ZDB-GENE-030131-6695
- Name
- sarcoglycan, beta (dystrophin-associated glycoprotein)
- Symbol
- sgcb Nomenclature History
- Previous Names
-
- fa03a05
- wu:fa03a05
- zgc:110833 (1)
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Localizes to sarcolemma. Human ortholog(s) of this gene implicated in autosomal recessive limb-girdle muscular dystrophy type 2E and muscular dystrophy. Is expressed in somite and trunk musculature. Orthologous to human SGCB (sarcoglycan beta).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Dalla Barba et al., 2023
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal recessive limb-girdle muscular dystrophy type 2E | Alliance | Muscular dystrophy, limb-girdle, autosomal recessive 4 | 604286 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Beta-sarcoglycan | Sarcoglycan complex subunit protein |
|---|---|---|---|
|
UniProtKB:Q3ZB93
|
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-sgcb | monoclonal | IgG1 | Mouse |
|
Leica Microsystems Inc.
|
3 |
Plasmids
No data available