Gene
nolc1
- ID
- ZDB-GENE-030131-6349
- Name
- nucleolar and coiled-body phosphoprotein 1
- Symbol
- nolc1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Involved in embryonic cranial skeleton morphogenesis. Predicted to localize to nucleolus and nucleoplasm. Used to study Treacher Collins syndrome. Is expressed in gut; head; immature eye; nervous system; and pectoral fin bud. Orthologous to human NOLC1 (nucleolar and coiled-body phosphoprotein 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 11 figures from 4 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| Treacher Collins syndrome | WT + MO1-nolc1 + MO2-nolc1 | standard conditions | Weiner et al., 2012 |
| Treacher Collins syndrome | WT + MO3-nolc1 | standard conditions | (2) |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | LIS1 homology motif | Nopp140-like | Srp40, C-terminal |
|---|---|---|---|---|
|
UniProtKB:A0A8M3B7S8
|
1000 | |||
|
UniProtKB:B8JIY2
|
1001 |
Interactions and Pathways
No data available
Plasmids
No data available