Gene

ift88

ID

ZDB-GENE-030131-574

Name

intraflagellar transport 88 homolog

Symbol

ift88 Nomenclature History

Previous Names

ovl
fb37b11
intraflagellar transport protein 88 (1)
oval
polaris (1)
ttc10 (1)
wu:fb37b11
xx:zah8127

Type

protein_coding_gene

Location

Chr: 9 Mapping Details/Browsers

Description

Predicted to have kinesin binding activity. Involved in several processes, including cilium organization; neuron development; and tissue homeostasis. Localizes to axoneme and ciliary basal body. Is expressed in forerunner cell group; head; nervous system; and pronephric duct. Orthologous to human IFT88 (intraflagellar transport 88).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

24 figures from 16 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 56 figures from 34 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ift88 Human Ortholog

No data available

Associated With ift88 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Homologous_superfamily	IPR011990	Tetratricopeptide-like helical domain superfamily
Repeat	IPR019734	Tetratricopeptide repeat

Domain Details Per Protein

Protein	Length	Tetratricopeptide-like helical domain superfamily	Tetratricopeptide repeat
UniProtKB:A0A8M9Q4H3 InterPro	842
UniProtKB:A0A8M9QJI0 InterPro	872
UniProtKB:A0A8M2BF03 InterPro	841
UniProtKB:A0A8M9PRW8 InterPro	856
UniProtKB:A0A8M2BEW9 InterPro	826
UniProtKB:A0A8M9QF86 InterPro	870
UniProtKB:A0A8M2BEY1 InterPro	857
UniProtKB:Q6RUQ9 InterPro	824

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	ift88-201 (1) Ensembl	Ensembl	2,941 nt	Select Tool ZFIN BLAST
mRNA	ift88-202 (1) Ensembl	Ensembl	3,431 nt	Select Tool ZFIN BLAST
mRNA	ift88-203 (1) Ensembl	Ensembl	602 nt	Select Tool ZFIN BLAST
mRNA	ift88-204 (1) Ensembl	Ensembl	3,386 nt	Select Tool ZFIN BLAST
mRNA	ift88-205 (1) Ensembl	Ensembl	2,388 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

Name	Type	Antigen Genes	Isotype	Host Organism	Assay	Source	Citations
Ab2-ift88		ift88		Rabbit	IHC		1
Ab1-ift88	polyclonal	ift88		Rabbit	IHC WB		15
Ab3-ift88	polyclonal	ift88	IgG	Rabbit	IHC	Proteintech	3

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations