Gene
rnf2
- ID
- ZDB-GENE-030131-5243
- Name
- ring finger protein 2
- Symbol
- rnf2 Nomenclature History
- Previous Names
-
- fa19h05
- ring1b
- wu:fa19h05
- wz4566 (1)
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to have chromatin binding activity and ubiquitin protein ligase activity. Involved in several processes, including animal organ morphogenesis; negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator; and pectoral fin development. Predicted to localize to MLL1 complex; PRC1 complex; and nuclear body. Is expressed in brain; eye; gonad; muscle; and pectoral fin. Orthologous to human RNF2 (ring finger protein 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6909582 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 29 figures from 6 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Luo-Schoch-Yamamoto syndrome | Alliance | Luo-Schoch-Yamamoto syndrome | 619460 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR017907 | Zinc finger, RING-type, conserved site |
| Domain | IPR001841 | Zinc finger, RING-type |
| Domain | IPR032443 | RAWUL domain |
| Domain | IPR037937 | E3 ubiquitin-protein ligase RING2, RAWUL domain |
| Family | IPR043540 | E3 ubiquitin-protein ligase RING1/RING2 |
| Homologous_superfamily | IPR013083 | Zinc finger, RING/FYVE/PHD-type |
Domain Details Per Protein
| Protein | Length | E3 ubiquitin-protein ligase RING1/RING2 | E3 ubiquitin-protein ligase RING2, RAWUL domain | RAWUL domain | Zinc finger, RING/FYVE/PHD-type | Zinc finger, RING-type | Zinc finger, RING-type, conserved site |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q803I4
|
336 | ||||||
|
UniProtKB:A0A0H2UKC6
|
338 |
Interactions and Pathways
No data available
Plasmids
No data available