Gene
cyp2x12
- ID
- ZDB-GENE-030131-4664
- Name
- cytochrome P450, family 2, subfamily X, polypeptide 12
- Symbol
- cyp2x12 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to have heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Predicted to be involved in several processes, including exogenous drug catabolic process; organic acid metabolic process; and xenobiotic metabolic process. Predicted to localize to cytoplasm and intracellular membrane-bounded organelle. Is expressed in liver.
- Genome Resources
- Note
-
There are alternate genes (haplotypes) in GRCz11: ENSDARG00000110311 and ENSDARG00000116677.
- Comparative Information
-
- All Expression Data
- 1 figure from Cheng et al., 2006
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cytochrome P450 | Cytochrome P450, conserved site | Cytochrome P450, E-class, group I | Cytochrome P450 family 2 | Cytochrome P450 superfamily |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A2R8S079
|
496 | |||||
|
UniProtKB:A0A1L1QZC0
|
496 | |||||
|
UniProtKB:A0A8M9PY44
|
496 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
cyp2x12-202
(1)
|
Ensembl | 1,694 nt | ||
| ncRNA |
si:dkey-286h2.7-003
(1)
|
Ensembl | 946 nt |
Interactions and Pathways
No data available
Plasmids
No data available