Gene
ddx41
- ID
- ZDB-GENE-030131-1927
- Name
- DEAD (Asp-Glu-Ala-Asp) box polypeptide 41
- Symbol
- ddx41 Nomenclature History
- Previous Names
-
- wu:fb92e02
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to have ATP binding activity; carbohydrate binding activity; and nucleic acid binding activity. Involved in NIK/NF-kappaB signaling; innate immune response; and response to virus. Localizes to cytoplasm and nucleus. Is expressed in brain; digestive system; gill; heart; and immune system. Orthologous to human DDX41 (DEAD-box helicase 41).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55896 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 12 figures from 3 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| {Myeloproliferative/lymphoproliferative neoplasms, familial (multiple types), susceptibility to} | 616871 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000922 | D-galactoside/L-rhamnose binding SUEL lectin domain |
| Domain | IPR001650 | Helicase, C-terminal domain-like |
| Domain | IPR001878 | Zinc finger, CCHC-type |
| Domain | IPR011545 | DEAD/DEAH box helicase domain |
| Domain | IPR014001 | Helicase superfamily 1/2, ATP-binding domain |
| Domain | IPR014014 | RNA helicase, DEAD-box type, Q motif |
| Domain | IPR044113 | DDX41, DEAD-box helicase domain |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| Homologous_superfamily | IPR043159 | D-galactoside/L-rhamnose binding SUEL lectin domain superfamily |
Domain Details Per Protein
| Protein | Length | DDX41, DEAD-box helicase domain | DEAD/DEAH box helicase domain | D-galactoside/L-rhamnose binding SUEL lectin domain | D-galactoside/L-rhamnose binding SUEL lectin domain superfamily | Helicase, C-terminal domain-like | Helicase superfamily 1/2, ATP-binding domain | P-loop containing nucleoside triphosphate hydrolase | RNA helicase, DEAD-box type, Q motif | Zinc finger, CCHC-type |
|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M6Z9J0
|
136 | |||||||||
|
UniProtKB:E9QFV1
|
222 | |||||||||
|
UniProtKB:A0A4P2L339
|
613 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available