Gene

trappc11

ID

ZDB-GENE-030131-1723

Name

trafficking protein particle complex subunit 11

Symbol

trappc11 Nomenclature History

Previous Names

c4orf41
fb78g05
fgr (1)
flj12716l
foie gras (1)
foigr
wu:fb78g05
zgc:136723
zgc:63684

Type

protein_coding_gene

Location

Chr: 14 Mapping Details/Browsers

Description

Involved in several processes, including Golgi organization; animal organ development; and protein N-linked glycosylation. Predicted to localize to Golgi apparatus. Used to study fatty liver disease. Human ortholog(s) of this gene implicated in autosomal recessive limb-girdle muscular dystrophy type 2S. Orthologous to human TRAPPC11 (trafficking protein particle complex 11).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7157127 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 17 figures from 7 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With trappc11 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
autosomal recessive limb-girdle muscular dystrophy type 2S	Alliance	Muscular dystrophy, limb-girdle, autosomal recessive 18	615356

Associated With trappc11 Via Experimental Models

Human Disease	Fish	Conditions	Citations
steatotic liver disease	trappc11^hi1532bTg	standard conditions	(2)
steatotic liver disease	trappc11^{hi1532bTg/hi1532bTg}	standard conditions	DeRossi et al., 2016

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR021773	Trafficking protein particle complex subunit 11
Domain	IPR025876	Trafficking protein particle complex subunit 11, C-terminal

Domain Details Per Protein

Protein	Length	Trafficking protein particle complex subunit 11	Trafficking protein particle complex subunit 11, C-terminal
UniProtKB:Q1RLX4 InterPro	1132
UniProtKB:A0A9U5BZX5 InterPro	1132

Transcripts

Genome Browsers

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	trappc11-201 (1) Ensembl	Ensembl		3,843 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

Name	Type	Antigen Genes	Isotype	Host Organism	Assay	Source	Citations
Ab1-trappc11	polyclonal	trappc11		Rabbit	WB		1

Plasmids

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations