Gene

nanos1

ID
ZDB-GENE-030131-1623
Name
nanos homolog 1
Symbol
nanos1 Nomenclature History
Previous Names
  • nos2 (1)
  • fb76c12
  • fb93h11
  • fb98e07
  • nanos-related gene (1)
  • wu:fb76c12
  • wu:fb93h11
  • wu:fb98e07
  • wu:fq21a10
Type
protein_coding_gene
Location
Chr: 14 Mapping Details/Browsers
Description
Predicted to have translation repressor activity. Involved in germ cell development and germ cell migration. Localizes to germ plasm and perinuclear region of cytoplasm. Human ortholog(s) of this gene implicated in spermatogenic failure 12. Is expressed in blastomere; cerebellum; hindbrain; midbrain hindbrain boundary; and primordial germ cell. Orthologous to several human genes including NANOS1 (nanos C2HC-type zinc finger 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
15 figures from 6 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Na et al., 2021
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With nanos1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
spermatogenic failure 12 Alliance Spermatogenic failure 12 615413
Associated With nanos1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR024161 Zinc finger, nanos-type
Family IPR008705 Nanos/Xcat2
Homologous_superfamily IPR038129 Nanos domain superfamily
Domain Details Per Protein
Protein Length Nanos domain superfamily Nanos/Xcat2 Zinc finger, nanos-type
UniProtKB:E7FDB3
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA nanos1-201 (1) Ensembl 2,426 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations