Gene
alox12
- ID
- ZDB-GENE-030131-1452
- Name
- arachidonate 12-lipoxygenase
- Symbol
- alox12 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Exhibits arachidonate 12(S)-lipoxygenase activity and calcium ion binding activity. Involved in oxidation-reduction process. Localizes to nucleus. Is expressed in several structures, including EVL; digestive system; epidermal cell; epidermis; and periderm. Orthologous to several human genes including ALOX12 (arachidonate 12-lipoxygenase, 12S type).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 10 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:64120 (10 images)
- IMAGE:7138147 (1 image)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR020834 | Lipoxygenase, conserved site |
| Domain | IPR001024 | PLAT/LH2 domain |
| Domain | IPR013819 | Lipoxygenase, C-terminal |
| Domain | IPR042062 | Lipoxygenase, vertebrates, PLAT domain |
| Family | IPR000907 | Lipoxygenase |
| Family | IPR001885 | Lipoxygenase, mammalian |
| Homologous_superfamily | IPR036226 | Lipoxigenase, C-terminal domain superfamily |
| Homologous_superfamily | IPR036392 | PLAT/LH2 domain superfamily |
Domain Details Per Protein
| Protein | Length | Lipoxigenase, C-terminal domain superfamily | Lipoxygenase | Lipoxygenase, conserved site | Lipoxygenase, C-terminal | Lipoxygenase, mammalian | Lipoxygenase, vertebrates, PLAT domain | PLAT/LH2 domain | PLAT/LH2 domain superfamily |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q7T2A9
|
670 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
alox12-201
(1)
|
Ensembl | 3,595 nt |
Interactions and Pathways
No data available
Plasmids