Gene
thbs4b
- ID
- ZDB-GENE-020708-4
- Name
- thrombospondin 4b
- Symbol
- thbs4b Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to have calcium ion binding activity and growth factor activity. Involved in tendon development. Predicted to localize to collagen-containing extracellular matrix; extracellular space; and sarcoplasmic reticulum. Is expressed in musculature system; pectoral fin; and somite. Orthologous to human THBS4 (thrombospondin 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 13 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:111910 (13 images)
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Subramanian et al., 2014
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR018097 | EGF-like calcium-binding, conserved site |
| Domain | IPR000742 | EGF-like domain |
| Domain | IPR001881 | EGF-like calcium-binding domain |
| Domain | IPR008859 | Thrombospondin, C-terminal |
| Domain | IPR024665 | Thrombospondin/cartilage oligomeric matrix protein, coiled-coil domain |
| Domain | IPR048287 | Thrombospondin-like, N-terminal domain |
| Domain | IPR049883 | NOTCH1 EGF-like calcium-binding domain |
| Homologous_superfamily | IPR013320 | Concanavalin A-like lectin/glucanase domain superfamily |
| Homologous_superfamily | IPR028974 | TSP type-3 repeat |
| Homologous_superfamily | IPR046970 | Thrombospondin/cartilage oligomeric matrix protein, coiled-coil domain superfamily |
| Repeat | IPR003367 | Thrombospondin, type 3-like repeat |
| Repeat | IPR017897 | Thrombospondin, type 3 repeat |
Domain Details Per Protein
| Protein | Length | Concanavalin A-like lectin/glucanase domain superfamily | EGF-like calcium-binding, conserved site | EGF-like calcium-binding domain | EGF-like domain | NOTCH1 EGF-like calcium-binding domain | Thrombospondin/cartilage oligomeric matrix protein, coiled-coil domain | Thrombospondin/cartilage oligomeric matrix protein, coiled-coil domain superfamily | Thrombospondin, C-terminal | Thrombospondin-like, N-terminal domain | Thrombospondin, type 3-like repeat | Thrombospondin, type 3 repeat | TSP type-3 repeat |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q8JGW0
|
949 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
thbs4b-201
(1)
|
Ensembl | 3,397 nt | ||
| ncRNA |
thbs4b-002
(1)
|
Ensembl | 822 nt |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab3-thbs4b | polyclonal | IgG | Rabbit |
|
GeneTex
|
5 | |
| Ab1-thbs4b | polyclonal | Rabbit |
|
4 |
Plasmids
No data available