Gene
flot1a
- ID
- ZDB-GENE-020430-1
- Name
- flotillin 1a
- Symbol
- flot1a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Predicted to enable protease binding activity. Predicted to be involved in several processes, including positive regulation of cell-cell adhesion mediated by cadherin; protein localization to plasma membrane; and regulation of endocytosis. Predicted to be located in endosome and membrane. Predicted to be part of flotillin complex. Predicted to be active in cytoplasmic vesicle and plasma membrane. Is expressed in nervous system; neural tube; and trigeminal placode. Orthologous to human FLOT1 (flotillin 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from von Philipsborn et al., 2005
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Moreno-Campos et al., 2024
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Band 7 domain | Band 7/SPFH domain superfamily | Flotillin, C-terminal domain | Flotillin family |
|---|---|---|---|---|---|
|
UniProtKB:Q7ZZ76
|
438 | ||||
|
UniProtKB:F1QEW4
|
423 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
flot1a-201
(1)
|
Ensembl | 3,796 nt | ||
| mRNA |
flot1a-202
(1)
|
Ensembl | 1,382 nt | ||
| mRNA | ottdart00000001801 (1) | Havana | 1,335 nt |
Interactions and Pathways
No data available
Plasmids
No data available