Gene

cct3

ID

ZDB-GENE-020419-5

Name

chaperonin containing TCP1, subunit 3 (gamma)

Symbol

cct3 Nomenclature History

Previous Names

chaperonin containing TCP1, subunit 3
chunp6930
no tectal neuron (1)
ntn (1)
wu:fb13f04 (1)
wu:fb52a02 (1)
wu:fj48b06 (1)

Type

protein_coding_gene

Location

Chr: 16 Mapping Details/Browsers

Description

Predicted to have ATP binding activity and unfolded protein binding activity. Involved in embryonic eye morphogenesis and negative regulation of retinal cell programmed cell death. Predicted to localize to chaperonin-containing T-complex. Orthologous to human CCT3 (chaperonin containing TCP1 subunit 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:64132 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 9 figures from 6 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With cct3 Human Ortholog

No data available

Associated With cct3 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR002194	Chaperonin TCP-1, conserved site
Family	IPR002423	Chaperonin Cpn60/GroEL/TCP-1 family
Family	IPR012719	T-complex protein 1, gamma subunit
Family	IPR017998	Chaperone tailless complex polypeptide 1 (TCP-1)
Family	IPR053374	TCP-1 chaperonin-containing T-complex
Homologous_superfamily	IPR027409	GroEL-like apical domain superfamily
Homologous_superfamily	IPR027410	TCP-1-like chaperonin intermediate domain superfamily
Homologous_superfamily	IPR027413	GroEL-like equatorial domain superfamily

Domain Details Per Protein

Protein	Length	Chaperone tailless complex polypeptide 1 (TCP-1)	Chaperonin Cpn60/GroEL/TCP-1 family	Chaperonin TCP-1, conserved site	GroEL-like apical domain superfamily	GroEL-like equatorial domain superfamily	T-complex protein 1, gamma subunit	TCP-1 chaperonin-containing T-complex	TCP-1-like chaperonin intermediate domain superfamily
UniProtKB:Q8JHI7 InterPro	543

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	cct3-201 (1) Ensembl	Ensembl	2,129 nt	Select Tool
ncRNA	cct3-002 (1) Ensembl	Ensembl	566 nt	Select Tool
ncRNA	cct3-003 (1) Ensembl	Ensembl	771 nt	Select Tool
ncRNA	cct3-004 (1) Ensembl	Ensembl	570 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

Name	Type	Antigen Genes	Isotype	Host Organism	Assay	Source	Citations
Ab1-cct3	monoclonal	cct3	IgG1 , k	Mouse	WB	Santa Cruz Biotechnology, Inc.	2

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations