Gene
odc1
- ID
- ZDB-GENE-010816-1
- Name
- ornithine decarboxylase 1
- Symbol
- odc1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to have ornithine decarboxylase activity. Involved in eye photoreceptor cell development. Predicted to localize to cytoplasm. Human ortholog(s) of this gene implicated in colorectal cancer. Is expressed in neuromast and ovary. Orthologous to several human genes including ODC1 (ornithine decarboxylase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 18 figures from 17 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55204 (1 image)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Bachmann-Bupp syndrome | 619075 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Binding_site | IPR022653 | Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site |
| Conserved_site | IPR022657 | Orn/DAP/Arg decarboxylase 2, conserved site |
| Domain | IPR022643 | Orn/DAP/Arg decarboxylase 2, C-terminal |
| Domain | IPR022644 | Orn/DAP/Arg decarboxylase 2, N-terminal |
| Family | IPR000183 | Ornithine/DAP/Arg decarboxylase |
| Family | IPR002433 | Ornithine decarboxylase |
| Homologous_superfamily | IPR009006 | Alanine racemase/group IV decarboxylase, C-terminal |
| Homologous_superfamily | IPR029066 | PLP-binding barrel |
Domain Details Per Protein
| Protein | Length | Alanine racemase/group IV decarboxylase, C-terminal | Orn/DAP/Arg decarboxylase 2, conserved site | Orn/DAP/Arg decarboxylase 2, C-terminal | Orn/DAP/Arg decarboxylase 2, N-terminal | Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site | Ornithine/DAP/Arg decarboxylase | Ornithine decarboxylase | PLP-binding barrel |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q9DGJ4
|
461 |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-odc1 | monoclonal | IgG2b | Mouse |
|
Sigma-Aldrich
|
3 |
Plasmids
No data available