Gene
arf1
- ID
- ZDB-GENE-010724-5
- Name
- ADP-ribosylation factor 1
- Symbol
- arf1 Nomenclature History
- Previous Names
-
- wu:fb33e02
- wu:fb78h01
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to have GTP binding activity. Involved in semicircular canal development. Predicted to localize to cytoplasm and plasma membrane. Human ortholog(s) of this gene implicated in periventricular nodular heterotopia. Is expressed in brain; head; pharyngeal arch 3-7; and semicircular canal. Orthologous to human ARF1 (ADP ribosylation factor 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55900 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Petko et al., 2009
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Periventricular nodular heterotopia 8 | 618185 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR005225 | Small GTP-binding domain |
| Family | IPR006689 | Small GTPase superfamily, ARF/SAR type |
| Family | IPR024156 | Small GTPase superfamily, ARF type |
| Family | IPR045872 | ADP-ribosylation factor 1-5 |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
Domain Details Per Protein
| Protein | Length | ADP-ribosylation factor 1-5 | P-loop containing nucleoside triphosphate hydrolase | Small GTPase superfamily, ARF/SAR type | Small GTPase superfamily, ARF type | Small GTP-binding domain |
|---|---|---|---|---|---|---|
|
UniProtKB:Q803D1
|
180 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids