Gene

cry1b

ID
ZDB-GENE-010426-3
Name
cryptochrome circadian regulator 1b
Symbol
cry1b Nomenclature History
Previous Names
  • cry1ab
  • cry1b
  • zcry1b (1)
  • fi26e03
  • wu:fi26e03 (1)
Type
protein_coding_gene
Location
Chr: 18 Mapping Details/Browsers
Description
Involved in negative regulation of transcription, DNA-templated. Localizes to nucleus. Human ortholog(s) of this gene implicated in advanced sleep phase syndrome. Is expressed in brain; eye; inner ear; liver; and ovary. Orthologous to human CRY1 (cryptochrome circadian regulator 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
15 figures from 11 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cry1b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
{Delayed sleep phase disorder, susceptibility to} 614163
Associated With cry1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain
Domain IPR006050 DNA photolyase, N-terminal
Family IPR002081 Cryptochrome/DNA photolyase class 1
Homologous_superfamily IPR014729 Rossmann-like alpha/beta/alpha sandwich fold
Homologous_superfamily IPR036134 Cryptochrome/DNA photolyase, FAD-binding domain-like superfamily
Homologous_superfamily IPR036155 Cryptochrome/photolyase, N-terminal domain superfamily
Domain Details Per Protein
Protein Length Cryptochrome/DNA photolyase class 1 Cryptochrome/DNA photolyase, FAD-binding domain Cryptochrome/DNA photolyase, FAD-binding domain-like superfamily Cryptochrome/photolyase, N-terminal domain superfamily DNA photolyase, N-terminal Rossmann-like alpha/beta/alpha sandwich fold
UniProtKB:Q7ZU27 606
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA cry1ab-201 (1) Ensembl 3,019 nt
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-cry1ab polyclonal Rabbit
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations