Gene

arnt2

ID

ZDB-GENE-001207-3

Name

aryl-hydrocarbon receptor nuclear translocator 2

Symbol

arnt2 Nomenclature History

Previous Names

arnt2X (1)
zfARNT2 (1)
chunp6921
unm t30256
unm_t30256
zfARNT2a (1)
zfARNT2b (1)
zfARNT2c (1)

Type

protein_coding_gene

Location

Chr: 7 Mapping Details/Browsers

Description

Exhibits DNA-binding transcription factor activity. Involved in several processes, including animal organ development; neuron differentiation; and response to hypoxia. Predicted to localize to nucleus. Is expressed in several structures, including gut; hatching gland; mandibular arch skeleton; nervous system; and vasculature. Orthologous to human ARNT2 (aryl hydrocarbon receptor nuclear translocator 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

8 figures from 5 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 21 figures from 11 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With arnt2 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		?Webb-Dattani syndrome	615926

Associated With arnt2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000014	PAS domain
Domain	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Domain	IPR013767	PAS fold
Family	IPR001067	Nuclear translocator
Family	IPR050933	Circadian Clock Transcription Factors
Homologous_superfamily	IPR035965	PAS domain superfamily
Homologous_superfamily	IPR036638	Helix-loop-helix DNA-binding domain superfamily
Repeat	IPR001610	PAC motif

Domain Details Per Protein

Protein	Length	Circadian Clock Transcription Factors	Helix-loop-helix DNA-binding domain superfamily	Myc-type, basic helix-loop-helix (bHLH) domain	Nuclear translocator	PAC motif	PAS domain	PAS domain superfamily	PAS fold
UniProtKB:A0A8M3B3V4 InterPro	723
UniProtKB:Q9DG12 InterPro	737
UniProtKB:A0A0R4ID51 InterPro	722
UniProtKB:A0A8M3ATW0 InterPro	738

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	arnt2-201 (1) Ensembl	Ensembl	2,296 nt	Select Tool
mRNA	arnt2-204 (1) Ensembl	Ensembl	6,666 nt	Select Tool
ncRNA	arnt2-003 (1) Ensembl	Ensembl	542 nt	Select Tool
ncRNA	arnt2-005 (1) Ensembl	Ensembl	2,080 nt	Select Tool
ncRNA	ottdart00000036705 (1) Ensembl	Ensembl	1,618 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

Name	Type	Antigen Genes	Isotype	Host Organism	Assay	Source	Citations
Ab1-arnt2	monoclonal	arnt2	IgG1	Mouse		Affinity BioReagents (Thermo Fisher Scientific)	2

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations