Gene

vtg1

ID

ZDB-GENE-001201-1

Name

vitellogenin 1

Symbol

vtg1 Nomenclature History

Previous Names

vg1
zfvg1 (1)
zgc:109796

Type

protein_coding_gene

Location

Chr: 22 Mapping Details/Browsers

Description

Exhibits antioxidant activity. Involved in cellular response to estrogen stimulus; response to estradiol; and response to xenobiotic stimulus. Predicted to localize to integral component of membrane. Is expressed in several structures, including adipose tissue; atrium; liver; pleuroperitoneal region; and unfertilized egg.

Genome Resources

Note

vtg1-201 is a transcript described in ZDB-PUB-180609-20 and matches ENSDART00000078276 (Zv9) and corresponds to the partial cDNA clone with sequence BC094995.

Comparative Information

Expression

All Expression Data

53 figures from 37 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 5 figures from Yilmaz et al., 2019
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With vtg1 Human Ortholog

No data available

Associated With vtg1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001747	Vitellogenin, N-terminal
Domain	IPR015255	Vitellinogen, open beta-sheet
Domain	IPR015258	Vitellinogen, beta-sheet shell
Family	IPR050733	Vitellogenin/Apolipophorin
Homologous_superfamily	IPR011030	Lipovitellin-phosvitin complex, superhelical domain
Homologous_superfamily	IPR015816	Vitellinogen, beta-sheet N-terminal
Homologous_superfamily	IPR015817	Vitellinogen, open beta-sheet, subdomain 1
Homologous_superfamily	IPR015819	Lipid transport protein, beta-sheet shell
Homologous_superfamily	IPR037088	Vitellinogen, beta-sheet shell domain superfamily

Domain Details Per Protein

Protein	Length	Lipid transport protein, beta-sheet shell	Lipovitellin-phosvitin complex, superhelical domain	Vitellinogen, beta-sheet N-terminal	Vitellinogen, beta-sheet shell	Vitellinogen, beta-sheet shell domain superfamily	Vitellinogen, open beta-sheet	Vitellinogen, open beta-sheet, subdomain 1	Vitellogenin/Apolipophorin	Vitellogenin, N-terminal
UniProtKB:Q1LWN2 InterPro	1362
UniProtKB:A0A8M3AME1 InterPro	1347

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	vtg1-201 (1) Ensembl	Ensembl	4,415 nt	Select Tool ZFIN BLAST
ncRNA	vtg1-002 (1) Ensembl	Ensembl	990 nt	Select Tool ZFIN BLAST
ncRNA	vtg1-003 (1) Ensembl	Ensembl	917 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

Name	Type	Antigen Genes	Isotype	Host Organism	Assay	Source	Citations
Ab1-vtg1	polyclonal	vtg1	IgG	Rabbit			1

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations