Gene

bmal1a

ID

ZDB-GENE-000509-1

Name

basic helix-loop-helix ARNT like 1a

Symbol

bmal1a Nomenclature History

Previous Names

bmal1
bmal1a (1)
zfBMAL1 (1)
arntl1a (1)
hif1b (1)
wu:fa04g03 (1)

Type

protein_coding_gene

Location

Chr: 25 Mapping Details/Browsers

Description

Exhibits transcription regulatory region sequence-specific DNA binding activity. Contributes to DNA binding activity. Involved in several processes, including circadian rhythm; photoperiodism; and regulation of transcription, DNA-templated. Localizes to transcription factor complex. Orthologous to human ARNTL (aryl hydrocarbon receptor nuclear translocator like).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

22 figures from 16 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:55263 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 2 figures from Jensen et al., 2012
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With bmal1a Human Ortholog

No data available

Associated With bmal1a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000014	PAS domain
Domain	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Domain	IPR013767	PAS fold
Family	IPR001067	Nuclear translocator
Family	IPR050933	Circadian Clock Transcription Factors
Homologous_superfamily	IPR035965	PAS domain superfamily
Homologous_superfamily	IPR036638	Helix-loop-helix DNA-binding domain superfamily
Repeat	IPR001610	PAC motif

Domain Details Per Protein

Protein	Length	Circadian Clock Transcription Factors	Helix-loop-helix DNA-binding domain superfamily	Myc-type, basic helix-loop-helix (bHLH) domain	Nuclear translocator	PAC motif	PAS domain	PAS domain superfamily	PAS fold
UniProtKB:Q9I879 InterPro	626

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	arntl1a-201 (1) Ensembl	Ensembl	2,343 nt	Select Tool
mRNA	arntl1a-202 (1) Ensembl	Ensembl	2,326 nt	Select Tool
mRNA	arntl1a-203 (1) Ensembl	Ensembl	1,881 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

Name	Type	Antigen Genes	Isotype	Host Organism	Assay	Source	Citations
Ab1-arntl1a	polyclonal	bmal1a		Rabbit			1

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations