Gene
dazl
- ID
- ZDB-GENE-000405-6
- Name
- deleted in azoospermia-like
- Symbol
- dazl Nomenclature History
- Previous Names
-
- zDAZL
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Exhibits mRNA 3'-UTR binding activity; sequence-specific DNA binding activity; and translation activator activity. Involved in 3'-UTR-mediated mRNA stabilization and negative regulation of gene silencing by miRNA. Localizes to cytoplasm. Is expressed in blastodisc; gonad; unfertilized egg; and yolk. Orthologous to several human genes including DAZL (deleted in azoospermia like).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 41 figures from 31 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 6 figures from Bertho et al., 2021
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| {Spermatogenic failure, susceptibility to} |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000504 | RNA recognition motif domain |
| Domain | IPR037551 | DAZ, RNA recognition motif, vertebrates |
| Domain | IPR043628 | DAZ domain |
| Homologous_superfamily | IPR012677 | Nucleotide-binding alpha-beta plait domain superfamily |
| Homologous_superfamily | IPR035979 | RNA-binding domain superfamily |
Domain Details Per Protein
| Protein | Length | DAZ domain | DAZ, RNA recognition motif, vertebrates | Nucleotide-binding alpha-beta plait domain superfamily | RNA-binding domain superfamily | RNA recognition motif domain |
|---|---|---|---|---|---|---|
|
UniProtKB:Q9YGW7
|
229 | |||||
|
UniProtKB:Q1LUN6
|
229 | |||||
|
UniProtKB:A0A8M2BHE4
|
212 |
Interactions and Pathways
No data available
Plasmids