Gene
anos1b
- ID
- ZDB-GENE-000201-13
- Name
- anosmin 1b
- Symbol
- anos1b Nomenclature History
- Previous Names
-
- anosmin-1b (1)
- kal1b
- kal1.2
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Description
- Predicted to have peptidase inhibitor activity. Involved in posterior lateral line neuromast deposition. Predicted to localize to extracellular region. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 1 with or without anosmia. Is expressed in several structures, including brain; hair cell; sensory system; tail bud; and vertical myoseptum. Orthologous to human ANOS1 (anosmin 1).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 14 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
hypogonadotropic hypogonadism 1 with or without anosmia | Alliance | Hypogonadotropic hypogonadism 1 with or without anosmia (Kallmann syndrome 1) | 308700 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR003961 | Fibronectin type III |
Domain | IPR008197 | WAP-type 'four-disulfide core' domain |
Domain | IPR040957 | Anosmin-1, cysteine rich domain |
Family | IPR042447 | Anosmin-1 |
Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
Homologous_superfamily | IPR036116 | Fibronectin type III superfamily |
Homologous_superfamily | IPR036645 | Elafin-like superfamily |
Domain Details Per Protein
Protein | Length | Anosmin-1 | Anosmin-1, cysteine rich domain | Elafin-like superfamily | Fibronectin type III | Fibronectin type III superfamily | Immunoglobulin-like fold | WAP-type 'four-disulfide core' domain |
---|---|---|---|---|---|---|---|---|
UniProtKB:Q1MT36
|
633 |
Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
anos1b-201
(1)
|
Ensembl | 4,346 nt | ||
mRNA |
anos1b-202
(1)
|
Ensembl | 3,136 nt |
Interactions and Pathways
No data available
Plasmids
No data available