FIGURE

Fig. 5

ID

ZDB-FIG-241028-58

Publication

Wang et al., 2024 - The Xaliproden Nanoscale Zirconium-Porphyrin Metal-Organic Framework (XAL-NPMOF) Promotes Photoreceptor Regeneration Following Oxidative and Inflammatory Insults

Other Figures

All Figure Page

Back to All Figure Page

Fig. 5

Cell proliferation of phototoxicity-injured retinas following injection of XAL-NPMOF. (A) PCNA staining in sections taken from retinas at 1, 2, 3 and 4 dpl. (B) Statistical analysis of the area of PCNA-positive cells. There was a significantly larger area in the XAL-NPMOF group than in the PBS, NPMOF and XAL groups at 1 and 2 dpl (ANOVA, *p < 0.05). There were more PCNA-positive cells in the retinas of the NPMOF, XAL and XAL NPMOF groups than in those of the PBS group at 3 and 4 dpl (ANOVA, *p < 0.05). (C and D) The expression of ascl1a and sox2 mRNA at 36, 48 and 72 hpl (ANOVA, *p < 0.05). Scale bar in (A): 50 ?m. Abbreviations: dpl, days post lesion; hpl, hours post lesion; ONL, outer nuclear layer; INL, inner nuclear layer; GCL, ganglion cell layer.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Int. J. Nanomedicine