FIGURE

Fig. 5

ID

ZDB-FIG-240829-46

Publication

Hatchett et al., 2024 - Lowered GnT-I Activity Decreases Complex-Type N-Glycan Amounts and Results in an Aberrant Primary Motor Neuron Structure in the Spinal Cord

Other Figures

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Fig. 5

Mutant fish demonstrate delayed hatching and swim bladder development, and motor skill impairment. Bar graphs representing the percent (%) of embryos hatched at 72 hpf (left bars) and 78 hpf (right bars), while n denotes number of clutches (A), and the percent of swim bladders inflated at 5 dpf, while n signifies number of clutches (B). Movement in pixels acquired via the mean square difference (MSD) assay at 8 dpf, while n denotes the number of fish (C). Time in seconds that adult zebrafish could efficiently swim without being swept into the whirlpool as observed in the spinner task assay, n represents the number of fish (D). In all cases, Wt AB are shown in purple bars, and Mgat1b−/− in gold bars. Data are presented as mean ± SEM and were compared using Student’s t-test (*** p < 0.0001; ** p < 0.01; * p < 0.04).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	mgat1b^{ecu300/ecu300} (AB)
Observed In:	hatching swim bladder swimming behavior
Stage Range:	Protruding-mouth to Days 7-13

Phenotype Detail

Acknowledgments

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