Phenotypes of trpm7 mutants at embryonic and larval stages. (a–d) Phenotypes of trpm7 mutant embryos at 48 h post-fertilization (hpf). Lateral views of a wild-type (WT) sibling (a) and a mutant embryo (b). Superimposition of video frames showing traces of touch-evoked swimming of a wild-type sibling (c). A mutant embryo did not respond to touch (d). (e) The survival test of wild-type siblings and mutants. This result was not statistically significant by logrank test (p = .9). (f–h) Phenotypes of trpm7 mutants at 35 days post-fertilization (dpf). Lateral views of a wild-type sibling (f) and a mutant (g). Body length is defined by the distance from the snout tip to the base of the tail (h). (i) Body length of wild-type siblings and mutants at 35 dpf.
|