FIGURE

Fig. 6

ID

ZDB-FIG-240715-66

Publication

Banerjee et al., 2024 - Hypomyelinated vps16 Mutant Zebrafish Exhibit Systemic and Neurodevelopmental Pathologies

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Fig. 6

vps16(-/-) mutants at 7 dpf show significantly reduced habituation response to multiple high-intensity acoustic/tap stimuli compared with their siblings. (A) Line graph representing distance traveled by vps16 (-/-) larvae at 7 dpf during complete high-intensity multiple-tap paradigm comprising 10 high-intensity taps with 10 s interstimulus intervals (ISIs) (sibling in blue, vps16(-/-) in green). (B) Graph representing average distance moved by 7 dpf siblings (blue; n = 84) and vps16(-/-) (green; n = 78) larvae at each individual tap stimuli. (C) Box plots representing median distance traveled by 7 dpf siblings (blue; n = 84) and vps16(-/-) (green; n = 78) larvae in response to multiple-tap stimuli. “***” = p < 0.001. (D) First-order exponential decay curve representing average distance traveled by 7 dpf siblings (blue; n = 84) and vps16(-/-) (green; n = 78) larvae at each individual tap stimuli. “****” = p < 0.0001. Error bars indicate SEM

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	vps16^wsu4/wsu4 (AB)
Condition:	mechanical stress
Observed In:	habituation swimming behavior
Stage:	Days 7-13

Phenotype Detail

Acknowledgments

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