FIGURE

Fig. 4

ID

ZDB-FIG-240702-134

Publication

Meneghetti et al., 2020 - Zebrafish ambra1a and ambra1b Silencing Affect Heart Development

Other Figures

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Fig. 4

AMBRA1 morphant embryos display increased cell proliferation. (A) Representative images of phospho-histone H3 immunohistochemistry in WT and AMBRA1 morphant embryos at 9 hpf. Scale bar, 200 μm. (B) The numbers of proliferating cells were counted and compared between WT embryos, AMBRA1 morphant embryos, and AMBRA1 morphant embryos co-injected with hAMBRA1 or mutated hAMBRA1PXP mRNAs. For each condition, 10 embryos were analyzed, and the experiment was performed twice. Statistical analysis was performed using Student's t-test. *p < 0.05; ***p < 0.001; ****p < 0.0001. Color images are available online.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO1-ambra1a WT + MO1-ambra1b
Knockdown Reagents:	MO1-ambra1a MO1-ambra1b
Observed In:	cell population proliferation
Stage:	90%-epiboly

Phenotype Detail

Acknowledgments

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