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Fig. 2

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ZDB-FIG-240321-55
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Thakuri et al., 2023 - Gracilaria chorda subcritical-water extracts as ameliorant of insulin resistance induced by high-glucose in zebrafish and dexamethasone in L6 myotubes
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Fig. 2

Effect of HG on toxicity and glucose uptake of zebrafish larvae. A) survivability in different concentrations of glucose solution for 72 h; B) level of glucose uptake; C) fluorescence imaging of glucose uptake (2.0X). Zebrafish larvae were exposed to d-glucose solution (32, 65, and 130 mM) from 5 dpf to 8 dpf to induce IR to create a T2DM model. Data are presented as mean ± SE (n = 8) and analyzed by one-way analysis of variance followed by Dunnett test. ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001 vs. control. Abbreviations: HG; high glucose, T2DM; type 2 diabetes mellitus.

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