FIGURE

FIGURE 9

ID

ZDB-FIG-230916-17

Publication

DeMoya et al., 2023 - Sin3a associated protein 130 kDa, sap130, plays an evolutionary conserved role in zebrafish heart development

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FIGURE 9

sap130a shows an association with hdac1 and MZsin3ab mutants have SVs (A) Representative image of Tg(myl7:EGFP) and MZsap130a;hdac1^b382/+;Tg(myl7:EGFP) NV and SVs at 48hpf. (B) Representative image of Tg(myl7:EGFP) and MZsin3ab;Tg(myl7:EGFP) NV and SVs at 48hpf. (C) Quantification of heart phenotype proportions in Tg(myl7:EGFP), MZsap130a;Tg(myl7:EGFP), hdac1^b382/+;Tg(myl7:EGFP) and MZsap130a;hdac1^b382/+;Tg(myl7:EGFP). The p-values are fisher’s exact test. (D) Quantification of heart phenotype proportions in Tg(myl7:EGFP) and MZsin3ab;Tg(myl7:EGFP). The p-values are fisher’s exact test. V and A are ventricle and atria, respectively. Scale bar 100 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	hdac1^b382/+; twu34Tg sap130a^pt32a/pt32a; twu34Tg sin3ab^pt36a/pt36a; twu34Tg hdac1^b382/+; sap130a^pt32a/pt32a; twu34Tg
Observed In:	cardiac ventricle
Stage:	Long-pec

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Cell Dev Biol