FIGURE
Figure 6
- ID
- ZDB-FIG-230720-21
- Publication
- Mansur et al., 2023 - Dynamic regulation of inter-organelle communication by ubiquitylation controls skeletal muscle development and disease onset
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Figure 6
Morphological changes in vesicular trafficking compartments in Klhl40a deficient myofibers. Sar1a is increased and co-localized with PDI in Klhl40a deficiency. The number of PDI-positive foci is also increased in the absence of Klhl40a. The fraction of Sec23 and Tango1 positive foci is decreased in klhl40a mutant myofibers. Disruption of the Golgi architecture was observed in a fraction of Klhl40a deficient myofibers. Data are mean ± S.E.M (unpaired t-test, parametric) for each quantification. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
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