FIGURE

Figure 6

ID

ZDB-FIG-230430-18

Publication

Aranda-Martínez et al., 2023 - Chronodisruption and Loss of Melatonin Rhythm, Associated with Alterations in Daily Motor Activity and Mitochondrial Dynamics in Parkinsonian Zebrafish, Are Corrected by Melatonin Treatment

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Figure 6

Analysis of the genes and proteins involved in mitochondrial dynamics. Regarding fission, the following markers were analyzed: (A) Expression of mfn1 mRNA; (B) Expression of mfn2 mRNA and (C) levels of Mfn2 protein in the same experimental groups; (D) Expression of opa1 mRNA and (E) levels of Opa1 protein in the same experimental groups. Fusion markers analyzed were: (F) dyn2 mRNA expression; (G) drp1 mRNA expression; and (H) Drp1 protein levels in the same experimental groups. Data are presented as mean ± SEM. * p < 0.05 versus control; ** p < 0.01 vs. control; *** p < 0.001 vs. control; # p < 0.05 vs. aMT; ## p < 0.01 vs. aMT; ### p < 0.001 vs. aMT; $ p < 0.05; $$ p < 0.01 vs. MPTP; $$$ p < 0.001 vs. MPTP. One-way ANOVA with a Tukey’s post hoc test.

Expression Data

Genes:	dnm1l dynll2a mfn1b mfn2 opa1
Fish:	AB
Conditions:	chemical treatment by environment: melatonin chemical treatment by environment: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine chemical treatment by environment: melatonin
Anatomical Term:	whole organism
Stage:	Day 5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB
Conditions:	chemical treatment by environment: melatonin chemical treatment by environment: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine chemical treatment by environment: melatonin
Observed In:	whole organism
Stage:	Day 5

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Antioxidants (Basel)